Crestor works by reducing a certain enzyme within the body that produces cholesterol. It belongs to a class of medications called statins.
Cholesterol is a form of lipid, a waxy substance that helps your body make cells, vitamins, and certain hormones. It is not inherently bad. Your liver produces an enzyme that synthesizes cholesterol to help with the above healthy functions. Additional cholesterol is introduced to the body through certain foods like meat, poultry, and dairy products.
There are two types of cholesterol: high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs). LDLs carry cholesterol throughout the body, delivering cholesterol to cells that need it. HDLs carry excess LDLs back to the liver, where they are broken down and flushed from the body. While LDLs play a key role in cell health, they build up when the body has more cholesterol than the cells need. This buildup turns into plaque in the arteries (blood vessels). As plaque covers the artery walls, the blood vessels become narrow. This makes it harder for blood to flow through the body, which can lead to heart disease and heart failure.
Statins work by reducing the production of cholesterol in the liver, which lowers the overall cholesterol levels in the body. Not only do statins decrease levels of LDLs in the body, but they can also raise the level of HDLs in the body. In effect, they keep the body from making too much of the “bad” cholesterol that builds up in arteries while increasing the amount of “good” cholesterol that carries the “bad” out of the body. This dual action has been shown, along with diet and exercise, to lower overall cholesterol levels in patients effectively.
Crestor works Lower-Density Lipoprotein Expression in Hepatocytes, which Reduces High-density Lipoprotein LevelsThis mechanism can be workable with a cholesterol-reducing effect, but it’s more work with lowering "bad" cholesterol levels in the body. Lowering these "bad" levels can reduce the chances of getting heart disease and other complications. Lowering LDLs can also reduce the risk of getting a stroke, as high LDLs can increase the risk of having a heart attack. Finally, lowering "bad" cholesterol can reduce the severity of irregular heart beat.
Statins also can lower "good" cholesterol, which can provide heart health, without increasing "bad" cholesterol levels. This dual action has been shown with a statin and a cholesterol-reducing effect. Lowering "good" cholesterol has the benefit of decreasing “bad” cholesterol levels, and can reduce the risk of heart disease by 5-10% depending on the statin dose.
Note that while these work, they’re not sufficient guidelines to work with, for, or to lower "bad" cholesterol levels. In addition, a large body of scientific literature warns that a “bad" level of “good” cholesterol can be dangerous. This is not true with a statin. For example, a study of more than 1,100 patients with at least slightly elevated levels of “good” cholesterol found that “good” cholesterol was associated with an increased risk of cardiovascular events (such as heart disease and stroke) in the setting of high levels of “bad” cholesterol. A statin with a “bad” cholesterol level also could increase the risk of getting a heart attack. In addition, a statin with a “bad” level of “good” cholesterol can have "good" cholesterol levels that are higher than what is present in "bad” cholesterol.
A high-density lipoprotein (“HDL”) is also a measure of "good” cholesterol. While high "good" cholesterol can be important if you have at least mildly high "bad" cholesterol, it can also be important in patients with very high "good" cholesterol. A high-density lipoprotein (“HDL”) can also be important if you have a family history of high LDLs, including “bad” cholesterol. If you have a history of high LDLs or other metabolic problems, you may need to increased your cholesterol-lowering dose or change your diet.
A family history of high LDLs or other metabolic problems may also work best if the member of the same family is on a low-density lipoprotein (“LDPL”) diet. A LDPL diet can increase cholesterol levels in the blood, making it more difficult for patients to "get" an erection.
Crestor, containing rosuvastatin, is a widely prescribed statin medication for managing cholesterol levels. It lowers LDL (bad cholesterol) and triglycerides while raising HDL (good cholesterol), reducing the risk of cardiovascular complications such as heart attacks and strokes. It is a trusted choice for individuals at risk of heart disease or those with high cholesterol.
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See also:Medically reviewed by Jessica Swirble, PharmDLast updated on March 31, 2025
Drug Information| | |
Rosuvastatin is a medication classified as a statin, primarily used to lower cholesterol and triglyceride levels in the blood. It contains Ezallor as its active ingredient, which belongs to a class of drugs known for their lipid-lowering effects.
Rosuvastatin is used to treat conditions such as:
Rosuvastatin may also be used to help with some conditions such as:
This may be a prescription-only medication for your specific condition. Additionally, your doctor may order periodic bloodsmth tests to monitor your blood levels of your medication. If you are using Rosuvastatin to treat any of the conditions listed, you do so by reviewing them with your healthcare provider.
The information contained herein is not a substitute for professional medical advice, diagnosis, or treatment. You should always speak with a doctor before you start using a prescription and if you experience any adverse reactions, talk with a doctor with any regard for your medical history and medical history accompanying this product.
Dizziness or lightheadedness may occur if your condition is not treated. If you experience severe or prolonged dizziness, stop taking Ezallor and contact a healthcare provider immediately.
It is important to let your healthcare provider know that you are taking Ezallor.
In the US, you will be required to give one year before your insuranceixir of cholesterol-lowering medication, called Rosuvastatin, becomes available to you.
It is not available in your state.
You will be prescribed a statin you will take after you begin treatment with Ezallor.
Dizziness or lightheadedness may occur if you have drowsiness or confusion while you are taking Rosuvastatin.
In some cases, Rosuvastatin may interact with other medications. In some cases, you may experience kidney or liver problems as a result of taking medications that may interact with Rosuvastatin.
It is important to let your healthcare provider know that you are taking Rosuvastatin before you start treatment with Ezallor. If you experience severe or prolonged dizziness or dizziness, you may experience these symptoms within days of starting Rosuvastatin.
In addition, if you have a condition that affects the rhythm of the sperm, you may experience difficulty getting or keeping an erection in response to taking Rosuvastatin.
AstraZeneca today announced that it will commence sales of a generic version of its cholesterol-lowering drug Crestor (rosuvastatin) beginning on December 11, 2015.
The generic version of Crestor is a cholesterol-lowering medication, which helps reduce LDL cholesterol by approximately 80%. It is the second-best-selling drug in the United States and is the most prescribed drug in the country.
Crestor’s estimated worldwide annual sales are estimated at $20 billion, and it is available as a tablet, capsule, and injectable formulation.
Crestor is an example of an FDA-approved medication that has been used for more than 30 years to reduce the risk of cardiovascular diseases in people with high blood pressure. AstraZeneca believes this medication could be a breakthrough in the treatment of high cholesterol.
“By working together with our colleagues across the world to bring Crestor to market, we hope to enhance our commitment to improving the lives of individuals with high cholesterol,” said AstraZeneca President and Chief Executive Officer Pascal Soriot.
“We’re excited to have continued progress in this important area of clinical trial development, and we’re very proud of the continued investment that has been made in this important area.”
The results of a large Phase III study in patients with type 2 diabetes found Crestor was a significant treatment for high blood pressure in the majority of patients. The study was the first to evaluate Crestor’s effectiveness in lowering blood pressure in people with type 1 diabetes.
In addition, the study’s findings support a long-term safety and efficacy of Crestor in type 2 diabetes patients. The findings will be presented at the annual meeting of the American Diabetes Association.
“Our research supports the continued commitment to improving the lives of individuals with high cholesterol,” said Dr. Michael J. Geller, director of the National Institute of Allergy and Infectious Diseases and Chief Medical Officer of AstraZeneca Pharmaceuticals.
“By working together with AstraZeneca and our colleagues in this critical area, we hope to enhance our commitment to improving the lives of individuals with high cholesterol. By working together, we hope to improve our patient care and health outcomes,” he said. “By working together, we hope to enhance our commitment to improving the lives of individuals with high cholesterol. We are proud to be the first and only FDA-approved medication on the market for this treatment.”
The U. S. Food and Drug Administration (FDA) approved Crestor in November 1997, and it is the first non-FDA-approved statin approved for this indication. Crestor is currently marketed by AstraZeneca for the treatment of high blood pressure, cholesterol, and other lipid disorders.
For more information about Crestor and its uses, please visit the
.About Crestor
Crestor is a generic version of Crestor, an cholesterol-lowering medication, which is a statin primarily used to treat high blood pressure and high cholesterol. It was approved by the FDA in November 1997. The medication contains the same active ingredient as the branded Crestor, which is known as rosuvastatin. The active ingredient is sildenafil citrate, which is also the generic name for the medicine. In addition, Crestor is available in both tablets and capsules.
Crestor is available in the U.
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